Agentic AI for the optimal decision.
APEX is a multi-agent clinical decision support system that fuses angiography, clinical guidelines, digital twins, and cohort analytics so heart teams can commit to the right treatment strategy with the evidence in one place.
Sequential pipeline. Clear contracts.
Each agent has a specific clinical responsibility. The heart team can see exactly what informed each recommendation.
Ingest & Normalize
Patient record, imaging, and clinical context — normalized with full provenance on every data field.
Clinical Guidelines
Eligibility mapping based on current Clinical Guidelines with supporting citations and criteria tracking.
Digital Twin
Advanced clinical profiling to identify relevant patient characteristics and potential care paths.
Imaging
Per-vessel analysis with image-level markup and findings traceable to the source frame.
Cohort
Converts natural-language questions into SQL to retrieve contextual insights from clinical reference populations.
Heart-Team Report
One synthesized consensus with per-agent reasoning — available via PDF or secure data export.
Four specialized agents. One decision-ready report.
APEX orchestrates four AI agents working on the same patient simultaneously to provide a comprehensive, multi-dimensional clinical view.
Clinical Guideline eligibility with the citation attached.
Maps the patient profile to the latest clinical evidence to ensure care stays within established best practices.
- Automated eligibility assessment
- Class I / IIa / IIb / III with Level of Evidence
- Direct links to evidence-based citations
Stenosis detection the heart team can audit.
Localizes and measures stenoses on angiogram frames, ensuring every finding is verifiable against the source study.
- Per-vessel percent stenosis with confidence scores
- Complexity tiering and scoring
- Frame-level annotation traceable to source DICOM
Patient-matched clinical intelligence.
Surfaces contextual insights from extensive, high-fidelity data environments by matching your patient to similar clinical profiles.
- High-dimensional patient matching
- Curated clinical intelligence
- Transparent, evidence-driven insights
Ask the reference population a question.
Leverages real-world evidence to transform natural-language queries into actionable clinical insights across global reference populations.
- Dynamic natural language query engine
- Instant population-wide benchmarking
- Visualized real-world evidence trends
One synthesized consensus.
Consolidates signals from all four agents into a single structured consensus report for the heart team.
- Structured consensus agreement scores
- Full audit trail to source data
- Ready for multi-disciplinary review
Full consultation from your phone.
Secure clinician messenger access for rapid triage and real-time risk stratification.
- On-call consults in real-time
- ER rapid risk stratification
- Secure, HIPAA-compliant interface
Built for the people who own the decision.
APEX is deployed at the point where cardiovascular treatment decisions get made — by the clinicians who make them, the systems that standardize them, and the organizations that measure them.
Interventional cardiologists, cardiac surgeons, and heart-team coordinators who review complex CAD cases daily. APEX speeds consensus without removing judgment from the loop.
- Guideline check in seconds, not a chart review
- Digital twin survival data for the specific patient
- Auditable reasoning they can sign and defend
Cath-lab directors and cardiovascular service lines standardizing treatment decisions across sites — reducing variability, improving appropriateness metrics, and accelerating Heart Team throughput.
- Reduced inter-physician decision variability
- Structured output ready for quality reporting
- EHR-embeddable via SMART-on-FHIR & CDS Hooks
Payers measuring treatment decision appropriateness, and outcomes researchers running retrospective or prospective cohort studies. APEX's structured output is a data layer — not a black box.
- Publication-ready cohort tables & Kaplan-Meier curves
- Appropriateness scoring with guideline citations
- FHIR-exportable for downstream analytics
Meet your hospital's data posture — not the other way around.
Hosted (SaaS)
Cloud-hosted in a HIPAA-configured environment. Single sign-on. Role-based access control. Fastest path to pilot.
On-premise
For hospitals with data-residency or PHI-egress requirements. Runs on the hospital's own infrastructure.
System Integration
APEX connects to PACS systems, imaging archives, and EHR sidebars via CDS Hooks or SMART-on-FHIR, ensuring it lives wherever your data resides.
Bring APEX to your heart team.
Book a 30-minute walk-through. We'll run a de-identified case end-to-end in the live product — guideline check, digital twin, imaging, cohort, and consensus report.
Request a clinical walk-through